Found 23 matching trials
Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study NA This study is looking at outcomes in people with advanced cancers who have ...
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Peter MacCallum Cancer Centre
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Melanoma Metastasized to the Brain and Steroids PHASE2 This clinical trial is to clarify whether treatment with a checkpoint inhib...
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Herlev Universityhospital
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MEK162 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function PHASE1 This study is a phase I, multi-center, open-label, single oral dose, parall...
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DaVita Clinical Research-Denver
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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial PHASE2 This ComboMATCH patient screening trial is the gateway to a coordinated set...
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University of Alabama at Birmingham Cancer Center
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Binimetinib in Addition to Standard Chemotherapy in KRAS Mutated NSCLC. PHASE1 The aim is to determine the recommended phase 2 dose (RP2D) of binimetinib ...
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Universitaetsspital Basel
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StrataPATHâą (Precision Indications for Approved Therapies) PHASE2 StrataPATHâą is a non-randomized, open-label trial designed to explore effic...
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Florida Cancer Specialists - North
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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy PHASE2 The purpose of the study is to determine whether the ability of MEK162 to a...
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Pfizer Investigative Site
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Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial) PHASE2 This phase II ComboMATCH treatment trial compares the usual treatment alone...
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University of Alabama at Birmingham Cancer Center
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The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials PHASE4 The purpose of this clinical trial (called the FLOTILLA study) is to give c...
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St. Joseph's Hospital and Medical Center
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PF-07284892 in Participants With Advanced Solid Tumors PHASE1 The purpose of this first-in-patient, open label study is to determine the ...
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Mayo Clinic in Arizona - Phoenix
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